any mysql query/command works in that screen.
You can start with say phpmyadmin.
which will show you the query on certain functions.
Or read the manual:
http://us2.php.net/manual/en/It is not for the faint of heart.
For example if you wish to find people with more than 99 Private messages.
Enter the following in the screen.
SELECT COUNT(*) as PMs, u.USER_DISPLAY_NAME
FROM
ubbt_PRIVATE_MESSAGE_USERS pmu, ubbt_PRIVATE_MESSAGE_TOPICS pmt, ubbt_USERS u
WHERE pmu.TOPIC_ID=pmt.TOPIC_ID
AND pmu.USER_ID=u.USER_ID
GROUP BY pmu.USER_ID HAVING PMs>99
ORDER BY PMs DESC
Of course the ubbt prefix may need to be changed for your site.