yes, you can see on that first line the path is wrong, main.inc.php was moved to the include folders <img src="https://www.ubbcentral.com/boards/images/graemlins/smile.gif" alt="" />
change:
require ("/usr/local/apache/htdocs/isiboard/ubbthreads/main.inc.php");
to:
require ("../../includes/main.inc.php");
hmm.. I see now that path yu have is mostly your path, you'll at least need to include the /includes directory in it.