Navigation:

There are now so many settings in so many different areas, tabs within sections, multiple ways of getting to the same thing, it's very easy to get lost when trying to find what you want. How many posts do you see on here about "I know I've seen it but can't remember where it is..." or "where do I change this / that / the other...". Also, some settings are in the Admin profile which is the last place you'd think to look.

Member Management:

I also think that the Member Management should have the same access to the options in User Profile / Preferences. Anything that is available to a user in their profile or preferences should automatically be accessible to Administrators via the CP ( ...and an option to stop a user from editing their profile ).